Ciona robusta (formerly C. intestinalis) as a model of gut host-microbe interactions
Creasy A, Rosario K, Leigh BA, Dishaw LJ, Breitbart M. Unprecedented Diversity of ssDNA Phages from the Family Microviridae Detected within the Gut of a Protochordate Model Organism (Ciona robusta). Viruses. 2018 Jul 31;10(8). pii: E404. doi: 10.3390/v10080404. PubMed PMID: 30065169; PubMed Central PMCID: PMC6116155.
How do immune effectors influence the structure of the gut microbiome?
Our Research Focus
We work on VCBPs
Relationship between symbiosis and immunity
Host-microbe dialogue via innate receptors
The role(s) of adherent bacterial communities in the gut
Molecular phylogeny of immune response genes
Our research is supported by:
National Science Foundation (IOS and MCB)
National Institutes of Health (our collaboration with Dr. Groer in USF Nursing)
All Children’s Hospital Johns Hopkins Medicine Foundation (several studies)
University of South Florida College of Medicine Deans Office (several early studies in Ciona)