How do immune effectors influence the structure of the gut microbiome?
Our Research Focus
Additional collaborations involve projects studying how transkingdom dynamics shape virulence among pathobionts of the human microbiome. Stay tuned.
Secreted immune effectors e.g.,VCBPs
Our work involves both in vivo and in vitro experiments and is supported by the NSF.
Some of our phage work involves a collaboration with Dr. Mya Breitbart.
We are now investigating fungi as an important player in the maintenance of gut microbiome homeostasis. VCBP-C can bind both bacteria and fungi, and may shape interaction outcomes.
Relationship between symbiosis and immunity
Host-microbe dialogue via innate receptors
The role(s) of adherent bacterial communities in the gut
Molecular phylogeny of immune response genes
Our research is supported by:
National Science Foundation and the
National Institutes of Health
All Children’s Hospital Johns Hopkins Medicine Foundation (several studies)
University of South Florida College of Medicine Deans Office (several early studies in Ciona)