New Preprints! (under review)
Prophages regulate Shewanella fidelis 3313 motility and biofilm formation: implications for gut colonization dynamics in Ciona robusta. Ojas Natarajan, Susanne L Gibboney, Morgan N Young, Shen Jean Lim, Natalia Pluta, Celine G.F. Atkinson, Brittany A Leigh, Assunta Liberti, Eric D Kees, Mya Breitbart, Jeffrey A Gralnick and Larry J Dishaw. bioRxiv 2022.11.23.517592; doi: https://doi.org/10.1101/2022.11.23.517592
Prophages regulate Shewanella fidelis 3313 motility and biofilm formation: implications for gut colonization dynamics in Ciona robusta. Ojas Natarajan, Susanne L Gibboney, Morgan N Young, Shen Jean Lim, Natalia Pluta, Celine G.F. Atkinson, Brittany A Leigh, Assunta Liberti, Eric D Kees, Mya Breitbart, Jeffrey A Gralnick and Larry J Dishaw. bioRxiv 2022.11.23.517592; doi: https://doi.org/10.1101/2022.11.23.517592
Clicking on the "Ciona" tab will reveal our work specific to MODEL DEVELOPMENT, since adopting Ciona as a research model in 2009. To see the rest of our published efforts, click on the individual year(s). A comprehensive list can also be found on Pubmed.
Enter the name for this tabbed section: Ciona
Liberti A, Natarajan O, Atkinson CGF, Dishaw LJ. Secreted immunoglobulin domain effector molecules of invertebrates and management of gut microbial ecology. Immunogenetics. 2022 Feb;74(1):99-109. doi: 10.1007/s00251-021-01237-2. Epub 2022 Jan 6. PMID: 34988622
Liberti A, Leigh BA, Graham Z, Natarajan O, Dishaw LJ. A Role for Secreted Immune Effectors in Microbial Biofilm Formation Revealed by Simple In Vitro Assays. Methods Mol Biol. 2022;2421:127-140. doi: 10.1007/978-1-0716-1944-5_9. PMID: 34870816
Liberti A, Natarajan O, Atkinson CGF, Sordino P, Dishaw LJ. Reflections on the Use of an Invertebrate Chordate Model System for Studies of Gut Microbial Immune Interactions. Front Immunol. 2021 Feb 25;12:642687. doi: 10.3389/fimmu.2021.642687. eCollection 2021.
Liberti A, Cannon JP, Litman GW, Dishaw LJ. A Soluble Immune Effector Binds Both Fungi and Bacteria via Separate Functional Domains. Front Immunol. 2019 Mar 6;10:369. doi: 10.3389/fimmu.2019.00369. PubMed PMID: 30894858
Creasy A, Rosario K, Leigh BA, Dishaw LJ, Breitbart M. Unprecedented Diversity of ssDNA Phages from the Family Microviridae Detected within the Gut of a Protochordate Model Organism (Ciona robusta). Viruses. 2018 Jul 31;10(8). pii: E404. doi: 10.3390/v10080404. PubMed PMID: 30065169; PubMed Central PMCID: PMC6116155.
Leigh BA, Breitbart M, Oksanen HM, Bamford DH, Dishaw LJ. Genome Sequence of PM2-Like Phage Cr39582, Induced from a Pseudoalteromonas sp. Isolated from the Gut of Ciona robusta. Genome Announc. 2018 May 24;6(21). pii: e00368-18. doi: 10.1128/genomeA.00368-18. PubMed PMID: 29798916; PubMed Central PMCID:PMC5968719.
Liberti A, Zucchetti I, Melillo D, Skapura D, Shibata Y, De Santis R, Pinto MR, Litman GW, Dishaw LJ. Chitin protects the gut epithelial barrier in a protochordate model of DSS-induced colitis. Biol Open. 2018 Jan 17;7(1). pii: bio029355. doi: 10.1242/bio.029355. PubMed PMID: 29222175.
Leigh BA, Djurhuus A, Breitbart M, Dishaw LJ. The gut virome of the protochordate model organism, Ciona intestinalis subtype A. Virus Res. 2017 Nov 15;244:137-146. doi: 10.1016/j.virusres.2017.11.015. [Epub ahead of print] PubMed PMID: 29155033.
Leigh B, Karrer C, Cannon JP, Breitbart M, Dishaw LJ. Isolation and Characterization of a Shewanella Phage-Host System from the Gut of the Tunicate, Ciona intestinalis. Viruses. 2017 Mar 22;9(3). pii: E60. doi: 10.3390/v9030060. PubMed PMID: 28327522
Leigh BA, Liberti A, Dishaw LJ. Generation of Germ-Free Ciona intestinalis for Studies of Gut-Microbe Interactions. Front Microbiol. 2016 Dec 27;7:2092. doi:10.3389/fmicb.2016.02092.
Dishaw LJ, Leigh B, Cannon JP, Liberti A, Mueller MG, Skapura DP, Karrer CR, Pinto MR, De Santis R, Litman GW. Gut immunity in a protochordate involves a secreted immunoglobulin-type mediator binding host chitin and bacteria. Nat Commun. 2016 Feb 15;7:10617.
Liberti A, Leigh B, De Santis R, Pinto MR, Cannon JP, Dishaw LJ, Litman GW. An Immune Effector System in the Protochordate Gut Sheds Light on Fundamental Aspects of Vertebrate Immunity. Results Probl Cell Differ. 2015;57:159-73.
Dishaw LJ, Cannon JP, Litman GW, Parker W. Immune-directed support of rich microbial communities in the gut has ancient roots. Dev Comp Immunol. 2014 Nov;47(1):36-51.
Liberti A, Melillo D, Zucchetti I, Natale L, Dishaw LJ, Litman GW, De Santis R, Pinto MR. Expression of Ciona intestinalis variable region-containing chitin-binding proteins during development of the gastrointestinal tract and their role in host-microbe interactions. PLoS One. 2014 May 2;9(5):e94984.
Dishaw LJ, Flores-Torres J, Lax S, Gemayel K, Leigh B, Melillo D, Mueller MG, Natale L, Zucchetti I, De Santis R, Pinto MR, Litman GW, Gilbert JA. The gut of geographically disparate Ciona intestinalis harbors a core microbiota. PLoS One. 2014 Apr 2;9(4):e93386.
Dishaw LJ, Flores-Torres JA, Mueller MG, Karrer CR, Skapura DP, Melillo D, Zucchetti I, De Santis R, Pinto MR, Litman GW. A Basal chordate model for studies of gut microbial immune interactions. Front Immunol. 2012;3:96. Epub 2012 May 3. PubMed PMID: 22563328; PubMed Central PMCID: PMC3342567.
Dishaw LJ, Giacomelli S, Melillo D, Zucchetti I, Haire RN, Natale L, Russo NA, De Santis R, Litman GW, Pinto MR. A role for variable region-containing chitin-binding proteins (VCBPs) in host gut-bacteria interactions. Proc Natl Acad Sci U S A. 2011 108(40): 16747-52.
Liberti A, Leigh BA, Graham Z, Natarajan O, Dishaw LJ. A Role for Secreted Immune Effectors in Microbial Biofilm Formation Revealed by Simple In Vitro Assays. Methods Mol Biol. 2022;2421:127-140. doi: 10.1007/978-1-0716-1944-5_9. PMID: 34870816
Liberti A, Natarajan O, Atkinson CGF, Sordino P, Dishaw LJ. Reflections on the Use of an Invertebrate Chordate Model System for Studies of Gut Microbial Immune Interactions. Front Immunol. 2021 Feb 25;12:642687. doi: 10.3389/fimmu.2021.642687. eCollection 2021.
Liberti A, Cannon JP, Litman GW, Dishaw LJ. A Soluble Immune Effector Binds Both Fungi and Bacteria via Separate Functional Domains. Front Immunol. 2019 Mar 6;10:369. doi: 10.3389/fimmu.2019.00369. PubMed PMID: 30894858
Creasy A, Rosario K, Leigh BA, Dishaw LJ, Breitbart M. Unprecedented Diversity of ssDNA Phages from the Family Microviridae Detected within the Gut of a Protochordate Model Organism (Ciona robusta). Viruses. 2018 Jul 31;10(8). pii: E404. doi: 10.3390/v10080404. PubMed PMID: 30065169; PubMed Central PMCID: PMC6116155.
Leigh BA, Breitbart M, Oksanen HM, Bamford DH, Dishaw LJ. Genome Sequence of PM2-Like Phage Cr39582, Induced from a Pseudoalteromonas sp. Isolated from the Gut of Ciona robusta. Genome Announc. 2018 May 24;6(21). pii: e00368-18. doi: 10.1128/genomeA.00368-18. PubMed PMID: 29798916; PubMed Central PMCID:PMC5968719.
Liberti A, Zucchetti I, Melillo D, Skapura D, Shibata Y, De Santis R, Pinto MR, Litman GW, Dishaw LJ. Chitin protects the gut epithelial barrier in a protochordate model of DSS-induced colitis. Biol Open. 2018 Jan 17;7(1). pii: bio029355. doi: 10.1242/bio.029355. PubMed PMID: 29222175.
Leigh BA, Djurhuus A, Breitbart M, Dishaw LJ. The gut virome of the protochordate model organism, Ciona intestinalis subtype A. Virus Res. 2017 Nov 15;244:137-146. doi: 10.1016/j.virusres.2017.11.015. [Epub ahead of print] PubMed PMID: 29155033.
Leigh B, Karrer C, Cannon JP, Breitbart M, Dishaw LJ. Isolation and Characterization of a Shewanella Phage-Host System from the Gut of the Tunicate, Ciona intestinalis. Viruses. 2017 Mar 22;9(3). pii: E60. doi: 10.3390/v9030060. PubMed PMID: 28327522
Leigh BA, Liberti A, Dishaw LJ. Generation of Germ-Free Ciona intestinalis for Studies of Gut-Microbe Interactions. Front Microbiol. 2016 Dec 27;7:2092. doi:10.3389/fmicb.2016.02092.
Dishaw LJ, Leigh B, Cannon JP, Liberti A, Mueller MG, Skapura DP, Karrer CR, Pinto MR, De Santis R, Litman GW. Gut immunity in a protochordate involves a secreted immunoglobulin-type mediator binding host chitin and bacteria. Nat Commun. 2016 Feb 15;7:10617.
Liberti A, Leigh B, De Santis R, Pinto MR, Cannon JP, Dishaw LJ, Litman GW. An Immune Effector System in the Protochordate Gut Sheds Light on Fundamental Aspects of Vertebrate Immunity. Results Probl Cell Differ. 2015;57:159-73.
Dishaw LJ, Cannon JP, Litman GW, Parker W. Immune-directed support of rich microbial communities in the gut has ancient roots. Dev Comp Immunol. 2014 Nov;47(1):36-51.
Liberti A, Melillo D, Zucchetti I, Natale L, Dishaw LJ, Litman GW, De Santis R, Pinto MR. Expression of Ciona intestinalis variable region-containing chitin-binding proteins during development of the gastrointestinal tract and their role in host-microbe interactions. PLoS One. 2014 May 2;9(5):e94984.
Dishaw LJ, Flores-Torres J, Lax S, Gemayel K, Leigh B, Melillo D, Mueller MG, Natale L, Zucchetti I, De Santis R, Pinto MR, Litman GW, Gilbert JA. The gut of geographically disparate Ciona intestinalis harbors a core microbiota. PLoS One. 2014 Apr 2;9(4):e93386.
Dishaw LJ, Flores-Torres JA, Mueller MG, Karrer CR, Skapura DP, Melillo D, Zucchetti I, De Santis R, Pinto MR, Litman GW. A Basal chordate model for studies of gut microbial immune interactions. Front Immunol. 2012;3:96. Epub 2012 May 3. PubMed PMID: 22563328; PubMed Central PMCID: PMC3342567.
Dishaw LJ, Giacomelli S, Melillo D, Zucchetti I, Haire RN, Natale L, Russo NA, De Santis R, Litman GW, Pinto MR. A role for variable region-containing chitin-binding proteins (VCBPs) in host gut-bacteria interactions. Proc Natl Acad Sci U S A. 2011 108(40): 16747-52.
Enter the name for this tabbed section: 2022-23
S J Lim, W. Jithpratuck, K. Wasylik, P. Sriaroon, L.J. Dishaw. Associations of microbial diversity with age and other clinical variables among pediatric chronic rhinosinusitis (CRS) patients. Microorganisms. 2023 Feb 7;11(2):422. doi: 10.3390/microorganisms11020422. PMID: 36838387
Liberti A, Natarajan O, Atkinson CGF, Dishaw LJ. Secreted immunoglobulin domain effector molecules of invertebrates and management of gut microbial ecology. Immunogenetics. 2022 Feb;74(1):99-109. doi: 10.1007/s00251-021-01237-2. Epub 2022 Jan 6. PMID: 34988622
Liberti A, Leigh BA, Graham Z, Natarajan O, Dishaw LJ. A Role for Secreted Immune Effectors in Microbial Biofilm Formation Revealed by Simple In Vitro Assays. Methods Mol Biol. 2022;2421:127-140. doi: 10.1007/978-1-0716-1944-5_9. PMID: 34870816
Liberti A, Natarajan O, Atkinson CGF, Dishaw LJ. Secreted immunoglobulin domain effector molecules of invertebrates and management of gut microbial ecology. Immunogenetics. 2022 Feb;74(1):99-109. doi: 10.1007/s00251-021-01237-2. Epub 2022 Jan 6. PMID: 34988622
Liberti A, Leigh BA, Graham Z, Natarajan O, Dishaw LJ. A Role for Secreted Immune Effectors in Microbial Biofilm Formation Revealed by Simple In Vitro Assays. Methods Mol Biol. 2022;2421:127-140. doi: 10.1007/978-1-0716-1944-5_9. PMID: 34870816
Enter the name for this tabbed section: 2020-21
Liberti A, Natarajan O, Atkinson CGF, Sordino P, Dishaw LJ. Reflections on the Use of an Invertebrate Chordate Model System for Studies of Gut Microbial Immune Interactions. Front Immunol. 2021 Feb 25;12:642687. doi: 10.3389/fimmu.2021.642687. eCollection 2021.
González-Mercado VJ, Henderson WA, Sarkar A, Lim J, Saligan LN, Berk L, Dishaw L, McMillan S, Groer M, Sepehri F, Melkus GD. Changes in Gut Microbiome Associated With Co-Occurring Symptoms Development During Chemo-Radiation for Rectal Cancer: A Proof of Concept Study. Biol Res Nurs. 2020 Jul 23:1099800420942830. doi: 10.1177/1099800420942830. PMID: 32700552
Groer M, Miller EM, Sarkar A, Dishaw LJ, Dutra SV, Youn Yoo J, Morgan K, Ji M, Ho T. Predicted Metabolic Pathway Distributions in Stool Bacteria in Very-Low-Birth-Weight Infants: Potential Relationships with NICU Faltered Growth. Nutrients. 2020 May 8;12(5):1345. doi: 10.3390/nu12051345.PMID: 32397161
Groer MW, Miller EM, D'Agata A, Ho TTB, Dutra SV, Yoo JY, Yee AL, Gilbert JA, Dishaw LJ. Contributors to Dysbiosis in Very-Low-Birth-Weight Infants. J Obstet Gynecol Neonatal Nurs. 2020 May;49(3):232-242. doi: 10.1016/j.jogn.2020.02.003. Epub 2020 Apr 2.PMID: 32247727
Ho TTB, Kumar A, Louis-Jacques AF, Dishaw LJ, Yee AL, Groer MW. The development of intestinal dysbiosis in anemic preterm infants. J Perinatol. 2020 Jul;40(7):1066-1074. doi: 10.1038/s41372-020-0599-z. Epub 2020 Jan 28.PMID: 31992818
González-Mercado VJ, Henderson WA, Sarkar A, Lim J, Saligan LN, Berk L, Dishaw L, McMillan S, Groer M, Sepehri F, Melkus GD. Changes in Gut Microbiome Associated With Co-Occurring Symptoms Development During Chemo-Radiation for Rectal Cancer: A Proof of Concept Study. Biol Res Nurs. 2020 Jul 23:1099800420942830. doi: 10.1177/1099800420942830. PMID: 32700552
Groer M, Miller EM, Sarkar A, Dishaw LJ, Dutra SV, Youn Yoo J, Morgan K, Ji M, Ho T. Predicted Metabolic Pathway Distributions in Stool Bacteria in Very-Low-Birth-Weight Infants: Potential Relationships with NICU Faltered Growth. Nutrients. 2020 May 8;12(5):1345. doi: 10.3390/nu12051345.PMID: 32397161
Groer MW, Miller EM, D'Agata A, Ho TTB, Dutra SV, Yoo JY, Yee AL, Gilbert JA, Dishaw LJ. Contributors to Dysbiosis in Very-Low-Birth-Weight Infants. J Obstet Gynecol Neonatal Nurs. 2020 May;49(3):232-242. doi: 10.1016/j.jogn.2020.02.003. Epub 2020 Apr 2.PMID: 32247727
Ho TTB, Kumar A, Louis-Jacques AF, Dishaw LJ, Yee AL, Groer MW. The development of intestinal dysbiosis in anemic preterm infants. J Perinatol. 2020 Jul;40(7):1066-1074. doi: 10.1038/s41372-020-0599-z. Epub 2020 Jan 28.PMID: 31992818
Enter the name for this tabbed section: 2018-19
Yee AL, Miller E, Dishaw LJ, Gordon JM, Ji M, Dutra S, Ho TTB, Gilbert JA, Groer M. Longitudinal Microbiome Composition and Stability Correlate with Increased Weight and Length of Very-Low-Birth-Weight Infants. mSystems. 2019 Feb 26;4(1). pii: e00229-18. doi: 10.1128/mSystems.00229-18. PubMed PMID: 30834328
Liberti A, Cannon JP, Litman GW, Dishaw LJ. A Soluble Immune Effector Binds Both Fungi and Bacteria via Separate Functional Domains. Front Immunol. 2019 Mar 6;10:369. doi: 10.3389/fimmu.2019.00369. PubMed PMID: 30894858
Creasy A, Rosario K, Leigh BA, Dishaw LJ, Breitbart M. Unprecedented Diversity of ssDNA Phages from the Family Microviridae Detected within the Gut of a Protochordate Model Organism (Ciona robusta). Viruses. 2018 Jul 31;10(8). pii: E404. doi: 10.3390/v10080404. PubMed PMID: 30065169; PubMed Central PMCID: PMC6116155.
Leigh BA, Breitbart M, Oksanen HM, Bamford DH, Dishaw LJ. Genome Sequence of PM2-Like Phage Cr39582, Induced from a Pseudoalteromonas sp. Isolated from the Gut of Ciona robusta. Genome Announc. 2018 May 24;6(21). pii: e00368-18. doi: 10.1128/genomeA.00368-18. PubMed PMID: 29798916; PubMed Central PMCID:PMC5968719.
Liberti A, Zucchetti I, Melillo D, Skapura D, Shibata Y, De Santis R, Pinto MR, Litman GW, Dishaw LJ. Chitin protects the gut epithelial barrier in a protochordate model of DSS-induced colitis. Biol Open. 2018 Jan 17;7(1). pii: bio029355. doi: 10.1242/bio.029355. PubMed PMID: 29222175.
Leigh BA, Djurhuus A, Breitbart M, Dishaw LJ. The gut virome of the protochordate model organism, Ciona intestinalis subtype A. Virus Res. 2018 Jan 15;244:137-146. doi: 10.1016/j.virusres.2017.11.015. [Epub ahead of print] PubMed PMID: 29155033.
Liberti A, Cannon JP, Litman GW, Dishaw LJ. A Soluble Immune Effector Binds Both Fungi and Bacteria via Separate Functional Domains. Front Immunol. 2019 Mar 6;10:369. doi: 10.3389/fimmu.2019.00369. PubMed PMID: 30894858
Creasy A, Rosario K, Leigh BA, Dishaw LJ, Breitbart M. Unprecedented Diversity of ssDNA Phages from the Family Microviridae Detected within the Gut of a Protochordate Model Organism (Ciona robusta). Viruses. 2018 Jul 31;10(8). pii: E404. doi: 10.3390/v10080404. PubMed PMID: 30065169; PubMed Central PMCID: PMC6116155.
Leigh BA, Breitbart M, Oksanen HM, Bamford DH, Dishaw LJ. Genome Sequence of PM2-Like Phage Cr39582, Induced from a Pseudoalteromonas sp. Isolated from the Gut of Ciona robusta. Genome Announc. 2018 May 24;6(21). pii: e00368-18. doi: 10.1128/genomeA.00368-18. PubMed PMID: 29798916; PubMed Central PMCID:PMC5968719.
Liberti A, Zucchetti I, Melillo D, Skapura D, Shibata Y, De Santis R, Pinto MR, Litman GW, Dishaw LJ. Chitin protects the gut epithelial barrier in a protochordate model of DSS-induced colitis. Biol Open. 2018 Jan 17;7(1). pii: bio029355. doi: 10.1242/bio.029355. PubMed PMID: 29222175.
Leigh BA, Djurhuus A, Breitbart M, Dishaw LJ. The gut virome of the protochordate model organism, Ciona intestinalis subtype A. Virus Res. 2018 Jan 15;244:137-146. doi: 10.1016/j.virusres.2017.11.015. [Epub ahead of print] PubMed PMID: 29155033.
Enter the name for this tabbed section: 2016-17
Leigh BA, Djurhuus A, Breitbart M, Dishaw LJ. The gut virome of the protochordate model organism, Ciona intestinalis subtype A. Virus Res. 2017 Nov 15;244:137-146. doi: 10.1016/j.virusres.2017.11.015. [Epub ahead of print] PubMed PMID: 29155033. (final publication in January 2018)
Leigh B, Karrer C, Cannon JP, Breitbart M, Dishaw LJ. Isolation and Characterization of a Shewanella Phage-Host System from the Gut of the Tunicate, Ciona intestinalis. Viruses. 2017 Mar 22;9(3). pii: E60. doi: 10.3390/v9030060. PubMed PMID: 28327522
Leigh BA, Liberti A, Dishaw LJ. Generation of Germ-Free Ciona intestinalis for Studies of Gut-Microbe Interactions. Front Microbiol. 2016 Dec 27;7:2092. doi:10.3389/fmicb.2016.02092.
Dishaw LJ, Leigh B, Cannon JP, Liberti A, Mueller MG, Skapura DP, Karrer CR, Pinto MR, De Santis R, Litman GW. Gut immunity in a protochordate involves a secreted immunoglobulin-type mediator binding host chitin and bacteria. Nat Commun. 2016 Feb 15;7:10617.
Leigh B, Karrer C, Cannon JP, Breitbart M, Dishaw LJ. Isolation and Characterization of a Shewanella Phage-Host System from the Gut of the Tunicate, Ciona intestinalis. Viruses. 2017 Mar 22;9(3). pii: E60. doi: 10.3390/v9030060. PubMed PMID: 28327522
Leigh BA, Liberti A, Dishaw LJ. Generation of Germ-Free Ciona intestinalis for Studies of Gut-Microbe Interactions. Front Microbiol. 2016 Dec 27;7:2092. doi:10.3389/fmicb.2016.02092.
Dishaw LJ, Leigh B, Cannon JP, Liberti A, Mueller MG, Skapura DP, Karrer CR, Pinto MR, De Santis R, Litman GW. Gut immunity in a protochordate involves a secreted immunoglobulin-type mediator binding host chitin and bacteria. Nat Commun. 2016 Feb 15;7:10617.
Enter the name for this tabbed section: 2010-15
Liberti A, Leigh B, De Santis R, Pinto MR, Cannon JP, Dishaw LJ, Litman GW. An Immune Effector System in the Protochordate Gut Sheds Light on Fundamental Aspects of Vertebrate Immunity. Results Probl Cell Differ. 2015;57:159-73.
Litman GW, Dishaw LJ. Early histocompatibility: color the mechanism green and red. Curr Biol. 2015 Nov 2;25(21):R1042-3. doi:10.1016/j.cub.2015.09.053.
Fahsbender E, Rosario K, Cannon JP, Gulland F, Dishaw LJ, Breitbart M. Development of a Serological Assay for the Sea Lion (Zalophus californianus) Anellovirus, ZcAV. Nature Sci Rep. 2015 May 12;5:9637. doi: 10.1038/srep09637.
Zhang L, Li L, Guo X, Litman GW, Dishaw LJ, Zhang G. Massive expansion and functional divergence of innate immune genes in a protostome. Nature Sci Rep. 2015 Mar 3;5:8693. doi: 10.1038/srep08693.
Groer MW, Luciano AA, Dishaw LJ, Ashmeade TL, Miller E, Gilbert JA. Development of the preterm infant gut microbiome: a research priority. Microbiome. 2014 Oct 13;2:38. doi: 10.1186/2049-2618-2-38.
Dishaw LJ, Cannon JP, Litman GW, Parker W. Immune-directed support of rich microbial communities in the gut has ancient roots. Dev Comp Immunol. 2014 Nov;47(1):36-51.
Liberti A, Melillo D, Zucchetti I, Natale L, Dishaw LJ, Litman GW, De Santis R, Pinto MR. Expression of Ciona intestinalis variable region-containing chitin-binding proteins during development of the gastrointestinal tract and their role in host-microbe interactions. PLoS One. 2014 May 2;9(5):e94984.
Dishaw LJ, Flores-Torres J, Lax S, Gemayel K, Leigh B, Melillo D, Mueller MG, Natale L, Zucchetti I, De Santis R, Pinto MR, Litman GW, Gilbert JA. The gut of geographically disparate Ciona intestinalis harbors a core microbiota. PLoS One. 2014 Apr 2;9(4):e93386.
Dishaw LJ, Litman GW. Changing views of the evolution of immunity. Front Immunol. 2013 May 21;4:122.
Litman GW, Dishaw LJ. Histocompatibility: clarifying fusion confusion. Curr Biol. 2013 Oct 21;23(20):R934-5. doi: 10.1016/j.cub.2013.08.048. PubMed PMID: 24156816.
Dishaw LJ, Flores-Torres JA, Mueller MG, Karrer CR, Skapura DP, Melillo D, Zucchetti I, De Santis R, Pinto MR, Litman GW. A Basal chordate model for studies of gut microbial immune interactions. Front Immunol. 2012;3:96. Epub 2012 May 3. PubMed PMID: 22563328; PubMed Central PMCID: PMC3342567.
Dishaw LJ, Haire RN, Litman GW. The amphioxus genome provides unique insight into the evolution of immunity. Brief Funct Genomics. 2012 Mar;11(2):167-76. PubMed PMID: 22402506; PubMed Central PMCID: PMC3310213.
Dishaw LJ, Giacomelli S, Melillo D, Zucchetti I, Haire RN, Natale L, Russo NA, De Santis R, Litman GW, Pinto MR. A role for variable region-containing chitin-binding proteins (VCBPs) in host gut-bacteria interactions. Proc Natl Acad Sci U S A. 2011 108(40): 16747-52.
Dishaw LJ, Mueller MG, Haire RN, Litman GW. Transfection-based genomic readout for identifying rare transcriptional splice variants. Methods Mol Biol. 2011;748:243-54.
Dishaw LJ, Ota T, Mueller MG, Cannon JP, Haire RN, Gwatney NR, Litman RT, Litman GW. The basis for haplotype complexity in VCBPs, an immune-type receptor in amphioxus. Immunogenetics. 2010 Sep;62(9):623-31. Epub 2010 Jul 22.
Cannon JP, Dishaw LJ, Haire, RN, Litman RT, Ostrov DA, and Litman GW. 2010. Recognition of additional roles for immunoglobulin domains in immune function. Semin Immunol, 2010 Feb;22(1):17-24. Epub 2009 Dec 8. Review. PubMed PMID: 20004115
Enter the name for this tabbed section: Pre-2010
Dorsey, MJ., A. Petrovic, M.R. Morrow, L.J. Dishaw, J.W. Sleasman. 2009. FOXP3 expression following bone marrow transplantation for IPEX syndrome after reduced-intensity conditioning. Immunol Res, 44(1-3): 179-84.(PMID 19471859)
Dishaw, LJ., Litman, G.W. Invertebrate allorecognition: the origins of histocompatibility. 2009. Current Biology, Apr 14; 19(7): R286-288.
Dishaw, L.J. M. G. Mueller, N. Gwatney, J. P. Cannon, R. N. Haire, R. T. Litman, C. T. Amemiya, T. Ota, L. Rowen, G. Glusman, G, W. Litman. 2008. Genomic Complexity of the Variable Region-Containing Chitin-Binding Proteins in Amphioxus, BMC Genetics, Dec 1;9(1):78. (PMID: 19046437).
Zhang, Q., C.M. Zmasek, L.J. Dishaw, M.G. Mueller, Y. Ye, , G.W. Litman, A. Godzik. 2008. Novel genes dramatically alter regulatory network topology in amphioxus. Genome Biology, 9(8):R123. Epub 2008 Aug4 (PMID: 18680598).
Holland, L.Z. et al (Bf annotation community), 2008. The amphioxus genome illuminates vertebrate origins and cephalochordate biology. Genome Research, 18(7): 1100-11 (PMID 18562680).
Litman, G.W., L.J. Dishaw, J.P. Cannon, R.N. Haire, J.P. Rast. 2007. Alternative mechanisms of immune receptor diversity. Current Opinion in Immunology, 19(5): 526-534.
Litman G.W., J. P. Cannon, L. J. Dishaw, R. N. Haire, D. D. Eason, J. A. Yoder, J. Hernandez Prada, D. A. Ostrov. 2007. Immunoglobulin variable regions in molecules exhibiting characteristics of innate and adaptive immune receptors. Immunologic Research: Perspectives in Immunology. 38(1-3): 294-304.
Dishaw, L.J., M.L. Herrera, and C.H. Bigger. 2006. Characterization and phylogenetic analysis of a Cnidarian LMP X-like cDNA. Immunogenetics 58 (5-6): 454-464.
Litman, G.W., J.P. Cannon, and L.J. Dishaw. 2005. Reconstructing immune phylogeny: new perspectives, Nature Reviews Immunology 5(11): 866-879.
Dishaw, L.J., S. L. Smith, and C. H. Bigger. 2005. Characterization of a C3-like cDNA in a coral: phylogenetic implications. Immunogenetics 57(7): 535-548.
Kozmik, Z., M. Daube, E. Frei, B. Norman, L. Kos, L. J. Dishaw, M. Noll, and J. Piatigorsky. 2003. Role of Pax Genes in Eye Evolution: A Cnidarian PaxB Gene Uniting Pax2 and Pax6 Functions. Developmental Cell 5: 773-785. (Nov. Issue: Cover Photo).
Piatigorsky, J., B. Norman, L.J. Dishaw, L. Kos, J. Horwitz, P.J. Steinbach, and Z. Kozmik. 2001. J3-crystallin of the jellyfish lens: Similarity to saposins. Proceedings of the National Academy of Sciences. USA. 98(22): 12362-67.
*This website is not an official University of South Florida website. Only the Dishaw Lab is responsible for its content.
Our research is or has been supported by:
National Science Foundation and the
National Institutes of Health
All Children’s Hospital Johns Hopkins Medicine Foundation (several studies)
University of South Florida College of Medicine Deans Office (several early studies in Ciona)